Bystander or No Bystander for Gene Directed Enzyme Prodrug Therapy.docVIP

Molecules 2009, 14, 4517-4545; doi:10.3390/moleculeOPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Review Bystander or No Bystander for Gene Directed Enzyme Prodrug Therapy Gabi U. Dachs 1,*, Michelle A. Hunt 1, Sophie Syddall 2, Dean C. Singleton 2 and Adam V. Patterson 2 1 Angiogenesis and Cancer Research Group, University of Otago, Christchurch, PO Box 4345, Christchurch 8140, New Zealand; E-Mail: michelle.hunt@otago.ac.nz (M.A.H.) 2 Auckland Cancer Society Research Centre, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand; E-Mails: s.syddall@auc