Cellular and molecular pathogenesis of systemic lupus erythematosus lessons from animal models.docVIP

Pathak and Mohan Arthritis Research Therapy 2011,13:241 /content/13/5/241 RE VIE W Cellular and molecular pathogenesis of systemic lupus erythematosus: lessons from animal models Simanta Pathak and Chandra Mohan* Zealand Black (NZB) and New Zealand White (NZW) Abstract strains, called NZB/W F1, and its derivatives, such as NZM2328 and NZM2410, and the MRL/lpr and BXSB/ Yaa strains e goal of this review is to discuss the Systemic lupus erythematosus (SLE) is a complex disease characterized by the appearance of autoantibodies against nuclear antigens and t