原创力文档CD44CD24 immunophenotypes onclinicopathologic features of salivary glandsmalignant neoplasms.docVIP
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CD44CD24 immunophenotypes onclinicopathologic features of salivary glandsmalignant neoplasms
Soaveetal.DiagnosticPathology2013,8:29
/content/8/1/29
RESEARCH
OpenAccess
CD44/CD24immunophenotypeson
clinicopathologicfeaturesofsalivaryglands
malignantneoplasms
DaniloFigueiredoSoave1,Jo?oPauloOliveiradaCosta1,GiorgiaGobbidaSilveira1,RenataCarolinaFragaIanez2,
LucineiRobertodeOliveira1,SilviaVanessaLouren?o3andAlfredoRibeiro-Silva1*
Abstract
Background:SalivaryGlandsMalignantNeoplasms(SGMNs)accountfor3-6%ofheadandneckcancersand0.3%
ofallcancers.TumorcellsthatexpressCD44andCD24exhibitastem-cell-likebehavior.CD44isthebindingsitefor
hyaluronicacid,andCD24isareceptorthatinteractswithP-selecti
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