原创力文档Cerebral blood flow and glucose metabolism in healthy volunteers measured using a high-resolution PET scanner.docVIP
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Cerebral blood flow and glucose metabolism in healthy volunteers measured using a high-resolution PET scanner
Huismanetal.EJNMMIResearch2012,2:63
/content/2/1/63
ORIGINAL RESEARCH
OpenAccess
Cerebralbloodflowandglucosemetabolismin
healthyvolunteersmeasuredusinga
high-resolutionPETscanner
MarcCHuisman1?,LarissaWvanGolen2*?,NikieJHoetjes1,HenriNGreuter1,PatrickSchober3,
RichardGIjzerman2,MichaelaDiamant2andAdriaanALammertsma1
Abstract
Background:Positronemissiontomography(PET)allowsforthemeasurementofcerebralbloodflow(CBF;based
on[15O]H2O)andcerebralmetabolicrateofglucoseutilization(CMRglu;basedon[18F]-2-fluoro-2-deoxy-D-glucose
18
([ F]FDG)).Byusingkineticmodeling,quantitativeCBFandCMRglu values
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