Chemo-Enzymatic Synthesis of Ester-Linked Docetaxel-Monosaccharide Conjugates as Water-Soluble Prodrugs.docVIP

Molecules 2011, 16, 6769-6777; doi:10.3390/molecule OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article Chemo-Enzymatic Synthesis of Ester-Linked Docetaxel-Monosaccharide Conjugates as Water-Soluble Prodrugs Kei Shimoda * and Naoji Kubota Department of Chemistry, Faculty of Medicine, Oita University, 1-1 Hasama-machi, Oita 879-5593, Japan * Author to whom correspondence should be addressed; E-Mail: shimoda@med.oita-u.ac.jp; Tel.: +81-97-586-5606; Fax: +81-97-586-5619. Received: 24 June 2011; in revised form: 28 July 2011 / Accepted: 3 August 2011 / P