Chromatin, gene silencing and HIV latency.docVIP

Review Chromatin, gene silencing and HIV latency Hoi-Ping Mok and Andrew ML Lever Address: Department of Medicine, University of Cambridge, Addenbrooke’s Hospital, Cambridge CB2 2QQ, UK. Correspondence: Andrew ML Lever. Email: amll1@mole.bio.cam.ac.uk Published: 23 November 2007 Genome Biology 2007, 8:228 (doi:10.1186/gb-2007-8-11-228) The electronic version of this article is the complete one and can be found online at /2007/8/11/228 ? 2007 BioMed Central Ltd Abstract One of the cellular defenses against virus infection is the silencing of viral gene expression. There is evidence that