Combination therapy in hypertension An update.docVIP

Kalra et al. Diabetology Metabolic Syndrome 2010, 2:44 /content/2/1/44 REVIEW Open Access Combination therapy in hypertension: An updateReview Sanjay Kalra*1, Bharti Kalra2 and Navneet Agrawal3 Abstract Meticulous control of blood pressure is required in patients with hypertension to produce the maximum reduction in clinical cardiovascular end points, especially in patients with comorbidities like diabetes mellitus where more aggressive blood pressure lowering might be beneficial. Recent clinical trials suggest that the approach of using monotherapy for the control of hypertension is not