Combinatorial RNA interference in Caenorhabditis elegans reveals that redundancy between gene duplicates can be maintained for more than 80 million years of evolution.docVIP

Open Access Re rch 2006TischleretVoal.lumesea7, Issue 8, Article R69 Combinatorial RNA interference in Caenorhabditis elegans reveals that redundancy between gene duplicates can be maintained for more than 80 million years of evolution Julia Tischler*, Ben Lehner*?, Nansheng Chen? and Andrew G Fraser* Addresses: *The Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK. ?CRG-EMBL Systems Biology Program, Centre for Genomic Regulation, Barcelona, Spain. ?Molecular Biology and Biochemistry, Simon Fraser University, University Drive, Burnaby, British Columbia, V5A 1S6, Canada