Common promoter variants of the NDUFV2 gene do not confer susceptibility to schizophrenia in Han Chinese.docVIP

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Common promoter variants of the NDUFV2 gene do not confer susceptibility to schizophrenia in Han Chinese.doc

Common promoter variants of the NDUFV2 gene do not confer susceptibility to schizophrenia in Han Chinese

Zhangetal.BehavioralandBrainFunctions2010,6:75 /content/6/1/75 RESEARCH OpenAccess CommonpromotervariantsoftheNDUFV2gene donotconfersusceptibilitytoschizophreniain HanChinese WenZhang1,3,XiaogangChen2*,WeiGong1,4,JinsongTang2,LiwenTan2,HaoGuo1,5,Yong-GangYao1* Abstract Background:TheNADH-ubiquinoneoxidoreductaseflavoproteingene(NDUFV2),whichencodesa24kD mitochondrialcomplexIsubunit,hasbeenreportedtobepositivelyassociatedwithschizophreniaandbipolar disorderindifferentpopulations. Methods:Wegenotypedthepromotervariantsofthisgene(rs6506640andrs1156044)bydirectsequencingin 529unrelatedHanChinese

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