Comparative analysis of tandem repeats from hundreds of species reveals unique insights into centromere evolution.docVIP

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Comparative analysis of tandem repeats from hundreds of species reveals unique insights into centromere evolution.doc

Comparative analysis of tandem repeats from hundreds of species reveals unique insights into centromere evolution

Meltersetal.GenomeBiology2013,14:R10 /content/14/1/R10 RESEARCH OpenAccess Comparativeanalysisoftandemrepeatsfrom hundredsofspeciesrevealsuniqueinsightsinto centromereevolution Dani?lPMelters1,2*,KeithRBradnam1*,HughAYoung3,NatalieTelis1,2,MichaelRMay4,JGrahamRuby5, RobertSebra6,PaulPeluso6,JohnEid6,DavidRank6,JoséFernandoGarcia7,JosephLDeRisi5,8,TimothySmith9, ChristianTobias3,JeffreyRoss-Ibarra10*,IanKorf1*andSimonWLChan2,8 Abstract Background:Centromeresareessentialforchromosomesegregation,yettheirDNAsequencesevolverapidly.In mostanimalsandplantsthathavebeenstudied,centromerescontainmegabas

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