原创力文档Comparative proteomic analysis of normal and tumor stromal cells by tissue on chip based mass spectrometry (toc-MS).docVIP
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Comparative proteomic analysis of normal and tumor stromal cells by tissue on chip based mass spectrometry (toc-MS)
Escheretal.DiagnosticPathology2010,5:10
/content/5/1/10
SHORT REPORT
OpenAccess
Comparativeproteomicanalysisofnormaland
tumorstromalcellsbytissueonchipbasedmass
spectrometry(toc-MS)
NikoEscher1,GüntherErnst1,ChristianMelle1,AlexanderBerndt2,JoachimHClement3,KerstinJunker4,
KarlheinzFriedrich5,OrlandoGuntinas-Lichius6,FerdinandvonEggeling1*
Abstract
Incarcinomatissues,geneticandmetabolicchangesnotonlyoccuratthetumorcelllevel,butalsointhesur-
roundingstroma.Thiscarcinoma-reactivestromaltissueisheterogeneousandconsistse.g.ofnon-epithelialcells
suchasfibroblastsorfibrocytes,inflammatorycellsandv
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