Competition between pentoses and glucose during uptake and catabolism in recombinant Saccharomyces cerevisiae.docVIP

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Competition between pentoses and glucose during uptake and catabolism in recombinant Saccharomyces cerevisiae.doc

Competition between pentoses and glucose during uptake and catabolism in recombinant Saccharomyces cerevisiae

SubtilandBolesBiotechnologyforBiofuels2012,5:14 /content/5/1/14 RESEARCH OpenAccess Competitionbetweenpentosesandglucose duringuptakeandcatabolisminrecombinant Saccharomycescerevisiae ThorstenSubtilandEckhardBoles* Abstract Background:InmixedsugarfermentationswithrecombinantSaccharomycescerevisiaestrainsabletoferment D-xyloseandL-arabinosethepentosesugarsarenormallyonlyutilizedafterdepletionofD-glucose.Thishasbeen attributedtocompetitiveinhibitionofpentoseuptakebyD-glucoseaspentosesugarsaretakenupintoyeastcells byindividualmembersoftheyeasthexosetransporterfamily.Wewantedtoinvestigatewhether

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