Competition between pentoses and glucose during uptake and catabolism in recombinant Saccharomyces cerevisiae.docVIP
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Competition between pentoses and glucose during uptake and catabolism in recombinant Saccharomyces cerevisiae
SubtilandBolesBiotechnologyforBiofuels2012,5:14
/content/5/1/14
RESEARCH
OpenAccess
Competitionbetweenpentosesandglucose
duringuptakeandcatabolisminrecombinant
Saccharomycescerevisiae
ThorstenSubtilandEckhardBoles*
Abstract
Background:InmixedsugarfermentationswithrecombinantSaccharomycescerevisiaestrainsabletoferment
D-xyloseandL-arabinosethepentosesugarsarenormallyonlyutilizedafterdepletionofD-glucose.Thishasbeen
attributedtocompetitiveinhibitionofpentoseuptakebyD-glucoseaspentosesugarsaretakenupintoyeastcells
byindividualmembersoftheyeasthexosetransporterfamily.Wewantedtoinvestigatewhether
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