原创力文档Computational simulation of vasopressin secretion using a rat model of the water and electrolyte homeostasis.docVIP
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Computational simulation of vasopressin secretion using a rat model of the water and electrolyte homeostasis
Nadeauetal.BMCPhysiology2010,10:17
/1472-6793/10/17
RESEARCH ARTICLE
OpenAccess
Computationalsimulationofvasopressin
secretionusingaratmodelofthewaterand
electrolytehomeostasis
LouisNadeau,DanielleArbour,DidierMouginot*
Abstract
Background:Inmammals,vasopressin(AVP)isreleasedfrommagnocellularneuronsofthehypothalamuswhen
osmoticpressureexceedsafixedset-point.AVPparticipatestothehydromineralhomeostasis(HH)bycontrolling
waterexcretionatthelevelofthekidneys.OurcurrentunderstandingoftheHHandAVPsecretionistheresultof
avastamountofdatacollectedoverthefivepastdecades.Thisexperimentaldatawascollecte
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