Contributions of Epstein–Barr Nuclear Antigen 1 (EBNA1) to Cell Immortalization and Survival.docVIP

Viruses 2012, 4, 1537-1547; doi:10.3390/v4091537 OPEN ACCESS viruses ISSN 1999-4915 /journal/viruses Review Contributions of Epstein–Barr Nuclear Antigen 1 (EBNA1) to Cell Immortalization and Survival Lori Frappier Department of Molecular Genetics, University of Toronto, 1 Kings College Circle, Toronto, ON M5S 1A8, Canada; E-Mail: lori.frappier@utoronto.ca; Tel.: +1-416-946-3501; Fax: +1-416-978-6885 Received: 19 July 2012; in revised form: 14 August 2012 / Accepted: 27 August 2012 / Published: 13 September 2012 Abstract: Epstein–Barr virus (EBV) immortalizes host cells as part of its l