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Dual energy x-ray absorptiometry analysis contributes to the prediction of hip osteoarthritis progression.doc

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Dual energy x-ray absorptiometry analysis contributes to the prediction of hip osteoarthritis progression

Available online /content/11/6/R162 Research article Open Access Vol 11 No 6 Dual energy x-ray absorptiometry analysis contributes to the prediction of hip osteoarthritis progression Martha C Casta?o Betancourt1, Jacqueline C Van der Linden1, Fernando Rivadeneira2,4, Rianne M Rozendaal3, Sita M Bierma Zeinstra3, Harrie Weinans1 and Jan H Waarsing1 1Orthopaedic Research Laboratory, Erasmus Medical Center, Dr Mollewaterplein 50, 3000 CA, Rotterdam. The Netherlands 2Department of Internal Medicine, Erasmus Medical Center, Dr Mollewaterplein 50, 3000 CA, Rotterdam, The Netherlands 3Department of General Practice, Erasmus Medical Center, Dr. Mollewaterplein 50, 3000 CA, Rotterdam, The Netherlands 4Department of Epidemiology, Erasmus Medical Center, Dr. Mollewaterplein 50, 3000 CA, Rotterdam, The Netherlands Corresponding author: Jan H Waarsing, e.waarsing@erasmusmc.nl Received: 29 Jul 2009 Revisions requested: 19 Aug 2009 Revisions received: 28 Sep 2009 Accepted: 2 Nov 2009 Published: 2 Nov 2009 Arthritis Research Therapy 2009, 11:R162 (doi:10.1186/ar2845) This article is online at: /content/11/6/R162 ? 2009 Casta?o Betancourt et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction To determine if structural bone parameters Results The model that included the DXA variables was significantly better in predicting hip OA progression than the model with K-L score of the affected side alone (P 0.01). The addition of the differences in DXA parameters between the most affected and contralateral hip in the superior part of the femoral head, trochanteric and intertrochanteric area further improved the prediction of progression (P 0.05). K-L score of the affected side was still the mos