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Effectiveness of a Chinese herbal medicine preparation in the treatment of cough in uncomplicated upper respiratory tract infection a randomised double-blinded placebo-control trial.doc

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Effectiveness of a Chinese herbal medicine preparation in the treatment of cough in uncomplicated upper respiratory tract infection a randomised double-blinded placebo-control trial

Cough BioMedCentral Research Open Access Effectiveness of a Chinese herbal medicine preparation in the treatment of cough in uncomplicated upper respiratory tract infection: a randomised double-blinded placebo-control trial Wong WCW*1, Lee A1, Lam AT2, Li KT2, Leung CYM2, Leung PC3, Wong ELY3 and Tang JL1 Address: 1Department of Community and Family Medicine, the Chinese University of Hong Kong, Hong Kong SAR, China, 2Family Medicine Training Centre, Prince of Wales Hospital, New Territory East, Hong Kong SAR, China and 3Clinical Trial Centre, Institute of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China Email: Wong WCW* - cwwong@.hk; Lee A - alee@.hk; Lam AT - lamt@.hk; Li KT - philipli@.hk; Leung CYM - cleung@.hk; Leung PC - pingcleung@.hk; Wong ELY - lywong@.hk; Tang JL - jltang@.hk * Corresponding author Published: 22 June 2006 Received: 20 September 2005 Accepted: 22 June 2006 Cough 2006, 2:5 doi:10.1186/1745-9974-2-5 This article is available from: /content/2/1/5 ? 2006 WCW et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Rigorous scientific and well-designed clinical trials to evaluate the effect of traditional Chinese medicine (TCM) is lacking. We, therefore, designed this study to evaluate the effectiveness of a commonly used TCM preparation in treating acute cough of uncomplicated URTI in adults and to search for a safe, effective and affordable alternative treatment for this common condition. Methods: A randomised, double-blinded, placebo-control study comparing this TCM preparation with a placebo was conducted in 82 patients who attended the Family Medicine Training Centre, Prince of Wales Hospital, Hong Kong between November and