Effects of high volume saline enemas vs no enema during labour – The N-Ma Randomised Controlled Trial [ISRCTN43153145].docVIP

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Effects of high volume saline enemas vs no enema during labour – The N-Ma Randomised Controlled Trial [ISRCTN43153145].doc

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Effects of high volume saline enemas vs no enema during labour – The N-Ma Randomised Controlled Trial [ISRCTN43153145]

BMC Pregnancy and Childbirth BioMedCentral Research article Open Access Effects of high volume saline enemas vs no enema during labour – The N-Ma Randomised Controlled Trial [ISRCT Luis Gabriel Cuervo*1, María del Pilar Bernal2 and Natalia Mendoza3 Address: 1Universidad Javeriana, Clinical Epidemiology Research and Training Center, Colombia, 2Portland, OR, USA and 3División de Investigaciones, Universidad El Bosque, Bogotá D.C., Colombia Email: Luis Gabriel Cuervo* - lgcuervo@; María del Pilar Bernal - mapilarbernal@; Natalia Mendoza - natyt99@ * Corresponding author Published: 19 March 2006 Received: 16 June 2005 Accepted: 19 March 2006 BMC Pregnancy and Childbirth2006, 6:8 doi:10.1186/1471-2393-6-8 This article is available from: /1471-2393/6/8 ? 2006Cuervo et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Enemas are used during labour in obstetric settings with the belief that they reduce puerperal and neonatal infections, shorten labour duration, and make delivery cleaner for attending personnel. However, a systematic review of the literature found insufficient evidence to support the use of enemas. The objective of this RCT was to address an identified knowledge gap by determining the effect of routine enemas used during the first stage of labour on puerperal and neonatal infection rates. Methods: Design: RCT (randomised controlled trial; randomized clinical trial). Outcomes: Clinical diagnosis of maternal or neonatal infections, labour duration, delivery types, episiotomy rates, and prescription of antibiotics Setting: Tertiary care referral hospital at the Javeriana University (Bogotá, Colombia) that attended 3170 births during study peri