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Effects on management and outcome of severe sepsis and septic shock patients admitted to the intensive care unit after implementation of a sepsis program a pilot study.doc

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Effects on management and outcome of severe sepsis and septic shock patients admitted to the intensive care unit after implementation of a sepsis program a pilot study

Available online /content/13/5/R143 Research Open Access Vol 13 No 5 Effects on management and outcome of severe sepsis and septic shock patients admitted to the intensive care unit after implementation of a sepsis program: a pilot study Massimo Girardis1, Laura Rinaldi1, Lara Donno1, Marco Marietta2, Mauro Codeluppi3, Patrizia Marchegiano4, Claudia Venturelli5 and the Sopravvivere alla Sepsi group of the Modena- University Hospital 1Department of Anaesthesiology and Intensive Care, University of Modena and Reggio Emilia and University Hospital of Modena; L.go del Pozzo, Modena, 41100, ITALY 2Department of Haematology, University Hospital of Modena; L.go del Pozzo, Modena, 41100, ITALY 3Department of Infectious Diseases, University Hospital of Modena; L.go del Pozzo, Modena, 41100, ITALY 4Medical Direction, University Hospital of Modena; L.go del Pozzo, Modena, 41100, ITALY 5Microbiology and Virology Unit, University Hospital of Modena; L.go del Pozzo, Modena, 41100, ITALY Corresponding author: Massimo Girardis, girardis.massimo@unimo.it Received: 27 Sep 2008 Revisions requested: 25 Oct 2008 Revisions received: 23 May 2009 Accepted: 3 Sep 2009 Published: 3 Sep 2009 Critical Care 2009, 13:R143 (doi:10.1186/cc8029) This article is online at: /content/13/5/R143 ? 2009 Girardis et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction The application in clinical practice of evidence- based guidelines for the management of patients with severe sepsis/septic shock is still poor in the emergency department, while little data are available for patients admitted to the intensive care unit (ICU). The aim of this study was to evaluate the effect of an in-hospital sepsis program on the adherence to e