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Effects of moxibustion for constipation treatment a systematic review of randomized controlled trials.doc

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Effects of moxibustion for constipation treatment a systematic review of randomized controlled trials

Leeetal.ChineseMedicine2010,5:28 /content/5/1/28 REVIEW OpenAccess Effectsofmoxibustionforconstipationtreatment: asystematicreviewofrandomizedcontrolled trials MyeongSooLee1,2*,Tae-YoungChoi1,Ji-EunPark1,EdzardErnst2 Abstract Severalstudiesreportedthatmoxibustionwaseffectiveintreatingconstipation.Thissystematicreviewassessesthe clinicalevidencefororagainstmoxibustionfortreatingconstipation.Twelvedatabasesweresearchedfromtheir inceptiontoMarch2010.Onlyrandomizedclinicaltrials(RCTs)wereincludediftheycomparedmoxibustionwith placebo,shamtreatment,drugtherapyornotreatment.ThemethodologicalqualityoftheseRCTswasassessed withtheCochraneriskofbiasanalysis.AllthreeRCTsincludedinthestudyhadahighriskofbias.Twoincluded studiesfoundfavorableeffectsofmoxibustion.ThethirdRCTshowedsignificanteffectsinthemoxibustiongroup. GiventhatthemethodologicalqualityofallRCTswaspoor,theresultsfromthepresentreviewareinsufficientto suggestthatmoxibustionisaneffectivetreatmentforconstipation.Morerigorousstudiesarewarranted. Background theory,therearefourconstipationpatterns,namelydif- Chronic constipation is a prevalent health condition ferentiation constipation (including heat constipation), withpatientstypicallyhavingbowelmovementstwicea coldconstipation,qiconstipationanddeficiencyconsti- week or less for at least two consecutive weeks or pation.Thedrainingmethodemployingfiliformneedles longer.TheRomeIIcriteriadefinechronicconstipation is used to treat heat constipation and qi constipation onthebasisoftwoormoreofthefollowingsymptoms [7].Ingeneral,moxibustionisusedtotreatcoldconsti- atleast25%ofthetimeforatleast12weeksinthepre- pation,anddeficiencyconstipation[8]. ceding year: straining at defection, lumpy/hard stools, Apossibleexplanationisthattheheatstimulatesacu- sensations ofincompleteevacuationandthreeorfewer pointstherebyincreasingqicirculationandrelievingqi bowel movements per week [1]. Currently, there is no stagnation [9], leading toincreased frequency