Experimental Contagious Caprine Pleuropneumonia A Long Term Study on the Course of Infection and Pathology in a Flock of Goats Infected with Mycoplasma capricolum subsp. capripneumoniae.docVIP
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Experimental Contagious Caprine Pleuropneumonia A Long Term Study on the Course of Infection and Pathology in a Flock of Goats Infected with Mycoplasma capricolum subsp. capripneumoniae
Acta vet. scand. 2004, 45, 167-179.
Experimental Contagious Caprine Pleuropneumonia:
A Long Term Study on the Course of Infection and
Pathology in a Flock of Goats Infected with
Mycoplasma capricolum subsp. capripneumoniae
By H.O. Wesonga1,5, G. B?lske2, F. Thiaucourt3, C. Wanjohi4 and R. Lindberg5
1National Veterinary Research Centre, Kenya Agricultural Research Institute, Kikuyu, Kenya, 2National Veteri-
nary Institute, Uppsala, Sweden, 3CIRAD-EMVT, Santé Animale, Montpellier, France, 4Veterinary Laborato-
ries, Private bag, Kabete, Kenya, and 5Department of Biomedical Sciences and Veterinary Public Health, Divi-
sion of Pathology, Pharmacology and Toxicology, Faculty of Veterinary Medicine and Animal Science, Swedish
University of Agricultural Sciences, Uppsala, Sweden.
Wesonga HO, B?lske G, Thiaucourt F, Wanjohi C, Lindberg R: Experimental con-
tagious caprine pleuropneumonia: A long term study on the course of infection and
pathology in a ?ock of goats infected with Mycoplasma capricolum subsp. caprip-
neumoniae. Acta vet. scand. 2004, 45, 167-179. – Contagious caprine pleuropneumo-
nia (CCPP) is a major threat to goat farming in parts of Africa and Asia. It classically
causes acute high morbidity and mortality early in infection, but little is known of its
long term epizootiology and course. In this study, 10 goats were inoculated with My-
coplasma capricolum subsp. capripneumoniae (M. capripneumoniae) and then mixed
with 15 goats for contact transmission. The disease course was monitored in each goat
for 56-105 days, whereafter the goats were killed and necropsied. Varying features sig-
nifying infection occurred in altogether 17 goats (7 inoculated, 10 in-contact). Clinical
signs were severe in 8 goats but no fatalities occurred. Only 6 goats had serum antibody
titres against M. capripneumoniae in ELISA. Fourteen goats (5 inoculated, 9 in-contact)
had chronic pleuropulmonary lesions compatible with CCPP at necropsy and 7 of those
showe
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