Expressed sequence tag profiling identifies developmental and anatomic partitioning of gene expression in the mouse prostate.docVIP

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Expressed sequence tag profiling identifies developmental and anatomic partitioning of gene expression in the mouse prostate.doc

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Expressed sequence tag profiling identifies developmental and anatomic partitioning of gene expression in the mouse prostate

Open Access Re rch 2003AbbottetVoal.lumesea4, Issue 12, Article R79 Expressed sequence tag profiling identifies developmental and anatomic partitioning of gene expression in the mouse prostate Denise E Abbott*, Colin Pritchard*, Nigel J Clegg*, Camari Ferguson*, Ruth Dumpit*, Robert A Sikes? and Peter S Nelson*? Addresses: *Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA. ?Laboratory for Cancer Ontogeny and Therapeutics, Department of Biological Sciences, University of Delaware, Newark, DE 19716, USA . ?Divisionof Clinical Research, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA. Correspondence: Peter S Nelson. E-mail: pnelson@ Published: 28 November 2003 Received: 11 September 2003 Revised: 28 October 2003 Accepted: 12 November 2003 Genome Biology 2003, 4:R79 The electronic version of this article is the complete one and can be found online at /2003/4/12/R79 ? 2003 Abbott et al.; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the articles original URL. ExpressedmhToexfihesptetnhropteelarsoilosgn,isibofctoinaaort.lsequencemceahgaselstmaieonsinsdcmapilsetagaarnntntadsoiprofilingnogriefgnnamgneottwioucsintaehidentifiesonarahnmliydgashrlelasaytnomdfpdevelopmentalreopocdadiatehlsnioz,tlefosudgprfietuchcanielecrcstm.oiandoAnendlctaihltanatomicaioaonutntigrshitbaiicufmfteeepxcspartitioningpotitlrnhatgnantahstieeionrnpvsserigosahstroftoteasetgenecenraehhnaaatbnslexpressioneycbeoaebitedhtneaediofnbeterthdatriilotinnihuteyrgthedoohutfhsgmmousetrhuoadumiegetmhsaieoaprostatelxelianfdtgeeannnspecies.eiavtaeonmddeipvcareMucholop-tandein Abstract Background: The prostate gland is an organ with highly specialized functional attributes that serves to enhance the fertility of mammalian species. Much