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Fibrin glue in the treatment of anal fistula a systematic review.doc

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Fibrin glue in the treatment of anal fistula a systematic review

Annals of Surgical Innovation and Research BioMedCentral Review Open Access Fibrin glue in the treatment of anal fistula: a systematic review Roberto Cirocchi?1, Eriberto Farinella*?1, Francesco La Mura?1, Lorenzo Cattorini?1, Barbara Rossetti?1, Diego Milani?1, Patrizia Ricci?2, Piero Covarelli?3, Marco Coccetta?1, Giuseppe Noya?3 and Francesco Sciannameo?1 Address: 1Department of General Surgery, St Maria Hospital, Terni, University of Perugia, Perugia, Italy, 2Department of General and Emergency Surgery, St Maria Hospital, Perugia, University of Perugia, Perugia, Italy and 3Department of General and Oncology Surgery, St Maria Hospital, Perugia, University of Perugia, Perugia, Italy Email: Roberto Cirocchi - cirocchiroberto@yahoo.it; Eriberto Farinella* - eriberto.far@; Francesco La Mura - doctorfrank81@hotmail.it; Lorenzo Cattorini - cremesys@excite.it; Barbara Rossetti - babiross77@libero.it; Diego Milani - diemilani@; Patrizia Ricci - pattygoricci@; Piero Covarelli - piero.covarelli@med.unipg.it; Marco Coccetta - mcocc@yahoo.it; Giuseppe Noya - giuseppenoya@unipg.it; Francesco Sciannameo - chgeurtr@unipg.it * Corresponding author ?Equal contributors Published: 14 November 2009 Received: 20 February 2009 Accepted: 14 November 2009 Annals of Surgical Innovation and Research 2009, 3:12 doi:10.1186/1750-1164-3-12 This article is available from: /content/3/1/12 ? 2009 Cirocchi et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: New sphincter-saving approaches have been applied in the treatment of perianal fistula in order to avoid the risk of fecal incontinence. Among them, the fibrin glue technique is popular because of its simplicity and repeatability. The aim of this review is to co