Fibrosarcoma of the childhood mandible.docVIP

Head Face Medicine BioMedCentral Case report Open Access Fibrosarcoma of the childhood mandible Martin Gosau*1, Florian G Draenert2, Wolfgang A Winter2, J?rg Mueller- Hoecker3 and Oliver Driemel1 Address: 1Department of Cranio-Maxillo-Facial Surgery, University of Regensburg, Germany, 2Department of Cranio-Maxillo-Facial Surgery, Ludwig Maximilians University of Munich, Germany and 3Institute of Pathology, Ludwig Maximilians University of Munich, Germany Email: Martin Gosau* - martin.gosau@klinik.uni-regensburg.de; Florian G Draenert - draenert@; Wolfgang A Winter - wolfgang.winter@med.uni-muenchen.de; J?rg Mueller-Hoecker - jmueller-hoecker@med.uni-muenchen.de; Oliver Driemel - oliver.driemel@klinik.uni-regensburg.de * Corresponding author Published: 16 September 2008 Received: 18 April 2008 Accepted: 16 September 2008 Head Face Medicine 2008, 4:21 doi:10.1186/1746-160X-4-21 This article is available from: /content/4/1/21 ? 2008 Gosau et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract A case of low-grade intraosseous fibrosarcoma of the mandible in a 9-year-old girl is described. The patient underwent pre-surgical chemotherapy which was abandoned as unsuccessful after two cycles. Radical tumour resection and mandibular reconstruction with a titanium bar were performed 3 months after diagnosis. No adjuvant therapy was given and lymph node dissection was not performed. No signs of recurrences or metastasis have been observed after a follow up time of 3 years so far. This article is presented to document the rarity of fibrosarcomas in the jaws of children and emphasizes the possible changes in the appearance of radiological imaging under tumour progression. Introduction with