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9 Folding and binding Protein–nucleic acid interactions Web alert Philip E Bourne*, Judith Murray-Rust† and Katrina L Gill‡ A selection of World Wide Web sites relevant to papers Review on three-dimensional domain swapping published in this issue of Current Opinion in /Articles/Vol4/issue12/ Structural Biology. 5301/5301.short.html The importance of domain swapping in protein oligomers was Addresses first recognised by the Eisenberg group at UCLA. Although this *San Diego Supercomputing Centre, University of California San review is now a little dated, and many more examples are Diego, 9500 Gilman Drive, La Jolla, CA 92093-0537, USA; known, it still provides a clear background to how domain e-mail: bourne@ swapping can contribute both to the function of multisubunit † Crystallography Department, Birkbeck College, London WC1E 7HX, proteins and to the evolution of multidomain proteins. UK; e-mail: ubcg09j@mail.cryst.bbk.ac.uk ‡ School of Biochemistry and Genetics, The Medical School, University Domain swapping in G-protein-coupled receptor dimers of Newcastle upon Tyne, Newcastle upon Tyne NE2 4HH, UK; http://www.essex.ac.uk/bs/staff/reync/ds/dimer.html e-mail: k.l.gill@ncl.ac.uk Domain swapping is a very efficient method of forming Current Opinion in Structural Biology 2002, 12:9–10