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141 Theory and simulation Macromolecular assemblages Web alert Jeremy H Lakey*, Paul A Craig† and Judith Murray-Rust‡ A selection of World Wide Web sites relevant to reviews coordinates of your own interacting proteins or examine published in this issue of Current Opinion in Structural Biology. precalculated properties, such as hydrophobicity and electro- static potential, for several protein pairs. Addresses *School of Biochemistry and Genetics, The Medical School, University The ligand-gated ion channel database of Newcastle upon Tyne, Newcastle upon Tyne NE2 4HH, UK; http://www.pasteur.fr/recherche/banques/LGIC/LGIC.html e-mail: j.h.lakey@ncl.ac.uk There are currently 402 entries of ligand-gated ion channel † San Diego Supercomputing Center, University of California San Diego, subunits in this database, which is curated by Nicolas Le 9500 Gilman Drive, La Jolla, CA 92093-0537, USA; Novère at the Institut Pasteur. They fall into three main groups: e-mail: pcraig@ the Cys-loop receptor superfamily, ATP-gated channels and ‡Crystallography Department, Birkbeck College, London WC1E 7HX, UK; glutamate-activated cationic channels. Available data include e-mail: ubcg09j@mail.cryst.bbk.ac.uk sequences, sequence alignments and atomic coordinates of Current Opinion in Structural Biology 2002, 12:141–142 subunits or portions of subunits. There is one entry per gene,