《儿童骨髓异常增生综合征诊治-中国专家共识》的理解与实践.pdfVIP

中华实用儿科临床杂志2016 年8 月第31 卷第 15 期 Chin J App1 Clin Pediatr ,August 2016 ,Vol. 31 ,No. 15 .1125. B100d Transfus , 2011 , 27 ( 1 ): 46 - 50. D01: 10. 1007/s12288{)11 [30 J Reese JA ,Muthurajah DS ,Kremer Hovi昭a JA ,et al. Children and a- 0054 -6 dults with thrombotic thrombocytopenic purpura associated with severe , [28 J Cines DB ,Bussel JB ,Liebman HA ,et al. The lTP syndrome: pathogenic acquired Adamts l3 deficiency: comparison of incidence , demographic and clinical diversity[JJ. Blood ,2oo9 , 113 (26) :6511 -652 1. DOI: and clinical features[ JJ. Pediatr Blood Cancer ,2013 ,60( 10) : 1676 - 1O .1182/blood-2oo9{)1-129155. 1682. DOI: 10. loo2/pbc. 24612. [29 J Hassenpflug W A ,Budde U ,5ch时ppenheim 5 ,et al. Inherited throm (收稿日期:2016{)6-20) botic thrombocytopenic pu叩ura in children [ J J. 5emin Thromb (本文编辑:李建华) Hemost ,2014 ,40(4) :487 -492. D0 I:10.1055/s .oo34-1376152. 《儿童骨髓异常增生综合征诊治-中国专家共识》 的理解与实践 谢晓恬 2α泊65 上海，同济大学附属同济医院儿科 通信作者:谢晓恬.Email:xtxie@163.com 001: 10. 37ω/cma. j. issn. 2095- 428X. 2016.15. ∞2 [摘要] 儿童骨髓异常增生综合征(MDS) 发病率较低，临床诊治难度较大。近期中华医学会儿科学分会 血液学组推荐的《儿童骨髓增生异常综合征诊断与治疗-中国专家共识》是为提高我国临床对于儿童 MDS 的认 识和诊治疗效，促进相关研究等具有很高学术意义的指导性文件。为了有助于该专家共识的有效推广，现结合 近年国内外相关文献，归纳临床诊治方面的实践，以期对临床有一定参考价值。 [关键词] 骨髓异常增生综合征;诊断标准;造血干细胞移植;免疫抑制治疗 基金项目:上海市先进适宜技术推广项目 (2013SY073) Understanding and practice of the Chinese expert consensus for the diagnosis and tr四tment of childhood my- elodysplastic syndromes Xie Xiαotian Department of Pediatrics , Tongji Hospital ,Medical School , Tongji University ,Shanghai 2000日， China Corresponding αuthor:Xie Xiaotian ,Emαil: xtxie@ 163. com [ Abstract] Childhood myelodysplastic syndromes ( MDS) is a disease with lower inc陆配e and veηdifficult in clinical diagnosis and tre