毒理学课件Toxicology201312.pptVIP

Essentials of Toxicology 毒理学基础 第一节 毒理学概述 Section One Outline of Toxicology 毒理学Toxicology *传统定义： 研究外源化学物（xenobiotics)对生物体损害作用(adverse effects)及其机制的科学 *现代毒理学 研究外源因素（化学、物理和生物因素)对生物系统（living systems）的损害作用、生物学机制（biologic mechanisms）、安全性评价（safety evaluation）与危险性分析（risk analysis)的科学。 Toxicology can be de?ned as that branch of science that deals with poisons, and a poison can be de?ned as any substance that causes a harmful effect when administered, either by accident or design, to a living organism. By convention, toxicology also includes the study of harmful effects caused by phys