细菌性阴道病与早产、胎膜早破的相关性研究_0.docVIP

细菌性阴道病与早产、胎膜早破的相关性研究 作者：卢玉莲,王文杰,魏莉从,张风格 【关键词】 阴道病,细菌性;分娩;早产;胎膜早破 　　【摘要】 目的 了解细菌性阴道病（BV）与早产、胎膜早破的相关性。 方法 209例孕妇分为正常孕妇组96例、早产组36例、胎膜早破组77例，对阴道分泌物进行BV的检测，并追踪观察妊娠结局。结果 早产组及胎膜早破组BV发生率分别为27.78%和22.08%,均明显高于正常孕妇组（9.38%），差异有显著性（P＜0.05）。而早产组与胎膜早破组之间无明显差异（P＞0.05）。妊娠合并BV组宫腔感染、产褥感染、新生儿窒息、新生儿感染明显高于非BV组（P＜0.05）。结论 妊娠合并BV与早产、胎膜早破、宫腔感染、产褥感染、新生儿窒息、新生儿感染明显相关，有必要对妊娠妇女进行BV筛查和 治疗 。 【关键词】 阴道病，细菌性;分娩;早产;胎膜早破 Study on the relationship between bacterial vaginosis and preterm birth and premature rupture of membrane 【Abstract】 Objective To study the relationship between bacterial vaginosis（BV）of women at late pregnancy and preterm birth（PTB）and premature rupture of membrane（PROM）.Methods The vaginal delivery of 209 pregnant women at our hospital was enrolled,of which 96 were pregnant normally,36 with PTB and 77 had PROM.Bacterium culturing method was used to see if there occurred infection and the pregnancy process was observed continuously.Results The rate of BV was significantly lower in women gave normal birth than those of PTB（9.38% vs 27.78%,P＜0.05），and of PROM（9.38% vs 22.08%,P＜0.05）.But between group of PROM and PTB,the rates were not different significantly.The rates of intrauterine infection、puerperal infection、neonatal asphyxia、neonatal infection were significantly higher in BV group （P＜0.05）。Conclusion There is significant association between PTB、PROM、intrauterine infection、puerperal infection、neonatal asphyxia、neonatal infection and bacterial vaginopathy.So it is necessary to check-up and treat BV during pregnancy. 【Key words】 vaginosis,bacterial;parturition；premature birth; fatal membranes,premature rupture 细菌性阴道病（bacterial vaginosis,BV）是近年来新认识的一种性传播疾病，已成为育龄妇女最常见的阴道感染性疾病，占外阴阴道感染的40%~50%［1］，其患病人数远高于滴虫及真菌感染。近年来 研究 发现BV不仅与盆腔炎等妇科疾病有关，还可以引起羊膜腔感染、胎膜早破、产褥感染、低出生体重、新生儿感染及新生儿黄疸等导致不良围产结局［2,3］。2005年1~12月，我们对早产和胎膜早破与BV的关系进行了研究。现报告如下。 1 资料与方法 1.1 一般资料 随机抽取于2005年1~12月来我院就诊的早产36例，胎膜早破77例，以同期正常孕妇96例做对照进行BV检测，孕妇平均年龄为27.18岁。分为3组：正常孕妇组96例，早产组36例，胎膜早破组77例。 1.2 方法 用窥器暴露阴道了解白带情况，刮取阴道内4cm