中国放射性药物的现状与展望_贾红梅.pdfVIP

24 3 　　 Vol.24　No.3 2011 8 Journal of Isotopes Aug.2011 贾红梅, 刘伯里 (, , 　100875) :, (SPECT) (PET), (), 、, 、, 、 、。, , 、、 。 :;; : 615.42;R817　　:A 　　:1000-7512(2011)03-0129-11 Current Status and Prospects of Radiopharmaceuticals in China JIA Hong-mei, LIU Bo-li (K ey Laboratory of R ad iop harmaceutica ls (B eij ing N orma l University ), Min istry of E d uca tion , Colleg e of Chem istry , B eij ing N orm a l Un iversity , B eij ing 100875, Ch ina) Abstract:Radiopharmaceuticals could not only serve as effective diagnostic and therapeutic tools in human diseases, but also allow the assessment of metabolism and functional proces- ses by providing quick, non-invasive and real-time visualization of physiological and patho- logical processes in the living humans at the molecular level together with PET (positron e- mission tomography)and SPECT (single photon emission computed tomography)imaging modalities.They could provide new methods and new approaches of truly early diagnosis and therapy and possible pathways for the preventative medicine, translational medicine and personalized medicine.The present review provides an overview of current status of in vivo radiopharmaceuticals in China.Moreover, some prospects of research and development of radiopharmaceuticals in the near future was discussed.The addressed future trends include 99 131 188/186 the following aspects.(1)Production of medical radioisotopes including Mo, I, Re 123 and I.(2)Investigation on the basic radiopharmaceutical chemistry.(3)Development of receptor-based imaging agents.(4)Development of m