异搏定即维拉帕米(国外英文资料).doc

异搏定即维拉帕米 This is verapamil Verapamil, a derivative of the poppy base, was used as a coronary expansion in 1962. Verapamil is also known as the heteropyrine, amyl, a calcium channel blocker. In recent years, except for the treatment of hypertension, angina pectoris, arrhythmia, cerebrovascular disease, finger vasospasm, abdominal pain, loss of the esophagus delays disease, migraine, pulmonary hypertension, and prevent premature birth. The Chinese name of verapar is a name for the name VerapamilM, VerapamilM FC27H38N2O4M W454.6 cas54.6 2 characters 3 storage 4 function and purpose 5 pharmacological pharmacokinetic Six indications 7 usage. 8 adverse reactions 9 contraindications 10 drugs interact with each other 11 note 1 medicine editorial Molecular formula ingredients Cordilox, Iproveratril, Veraloc, Verapamilum IproveratrilISOPTIN 2 character editing tablets, needles. It is commonly used in the form of salt and white powder; Odourless. Dissolved in water in methanol, ethanol or chloroform. Melting point is 140 ℃ 145 ℃. The storage editor shades and keeps the secret. Action and purpose editing for calcium channel blockers (calcium antagonists). Because inhibiting the flow of calcium reduces the rate of automatic depolarization of heart diastolic, verapamil This slows the release of the sinus knot and slows the conduction. It can be slowed down to the conduction, and therefore can eliminate the room knot. Peripheral blood vessels have dilation, lowering blood pressure, but weaker, usually causing heart rate to slow down, but can also be accelerated by a drop in blood pressure. There is a diastolic effect on the coronary artery, which can increase the flow of coronary arteries and improve the oxygen supply of the heart muscle, and it also inhibits platelet aggregation. Pharmacodynamics of pharmacodynamics Belongs to the class Ⅳ anti-arrhythmic drugs, for flow in a calcium inhibitors (slow channel blockers), in the heart, calcium ion flow is suppressed in the sinoatria