浅谈乙肝五项定量检测模式(国外英文资料).docVIP

浅谈乙肝五项定量检测模式 Discuss the results of five quantitative tests of hepatitis b The infection of Heptitis B Virse (HBV) infection is worldwide, but the prevalence of HBV infection varies widely in different regions. Our country is a high prevalence area of HBV, and according to the latest data, the average population of HBsAg has fallen to 8.5%. HBV is transmitted mainly by blood and blood products, mother and child, broken skin and mucosa and sexual contact. Detection of hepatitis b infection and immune state of the common indexes for HBV serological sign including HBsAg, anti - HBs, HBeAg, anti - HBe, anti - HBc (that is, the so-called five) of hepatitis b and anti - HBc IgM, HBsAg positive HBV infection; Anti-hbs is a protective antibody, positive for HBV immunity, in hepatitis b and hepatitis b vaccine; HBsAg is revulva and anti-hbs, called HBsAg serology conversion. HBeAg positive can be used as an indicator of HBV replication and infectivity; Anti-hbe positive indicates low replication of HBV (with the exception of the former C). HBeAg is reyin and HBeAg, which is called HBeAg, is called HBeAg. Anti-hbc IgM positive prompts for HBV replication, often in the acute phase of hepatitis b; Anti-hbc total antibodies are mainly anti-hbc IgG, as long as they are infected with HBV, regardless of whether the virus is cleared. Currently using enzyme immunoassay (EIA) and radiation immunoassay (RIA), enzyme particles from analysis (MEIA) or chemiluminescence (CLIA) detection methods, such as detecting the five indicators. And chemiluminescence immunoassay because has the high sensitivity of ria, and enzyme-linked immune characteristics of easy operation, fast, easy to standardized operation, and tests do not use harmful reagent, reagent shelf life is long, therefore widely used in biology, medical research and clinical laboratory diagnosis work, become the one of the most promising method of radioactive immune analysis. With the deepening of the research and the advent of new