钙拮抗药(国外英文资料).docVIP

钙拮抗药(国外英文资料) Chapter 15 calcium antagonists Make love doctor Section 1 classification of calcium antagonist and the name of the drug (assistant not required) A selective calcium antagonist (1) paramamine and gallopamine. (zy2003-1-222) (2) dihydropyridine, nitrana, nemotipine, nihidipine, and ammoniac. (3) diltiotiazole. Two, non-selective calcium antagonists (1) piperazine fluorotriazine, quilizine. (2) punilamine. (3) other classes, pipericillin. Zy2003-1-222  the following belong to benzene alkyl amine selective calcium antagonist medicine is  A. nifedipine  B. verapamil  C. putney ramin  D. pp g yesterday  Lin E. flunarizine  Answer: B  The pharmacological function and clinical application of calcium antagonist in section 2 First, pharmacological action (a) of myocardial 1. The negative inotropic effect Calcium antagonist medicine can reduce myocardial intracellular Ca2 + content, cause negative inotropic effect, can reduce the myocardial oxygen consumption, combined with drugs cause vasodilation, decreased cardiac afterload, can make the myocardial oxygen consumption down further. The negative frequency and negative conduction slow response cells such as sinus node and atrial junction are associated with Ca2 + internal flow in the zero phase of the junction of the ventricular node and the atrial junction. There is a link between the polarization and conduction of 0, and the 4 phase of automatic depolarization and self-regulation. The calcium antagonist can inhibit the Ca2 + flow in these cases. Can cause negative frequency and negative conduction of atrioventricular node conduction slow, should not be extended, turn-back excitement disappeared, used in the treatment of paroxysmal ventricular sex on the room tachycardia. The calcium antagonist can reduce the self-regulation of the sinus knot, causing the heart rate to slow down. 3. The protection of myocardial ischemia Myocardial ischemia, the inhibition of sodium, calcium pump and calcium passive trans