2型糖尿病及其药物对心房颤动影响.pdfVIP

!坠查笪痘堂堂屋兰Q!鱼生Z旦箜!!鲞笠兰塑丛生鱼型迎箜!旦鱼：丛!Q!鱼：堕!：12：丛：垒 ·337· 2型糖尿病及其药物对心房颤动的影响 张若愚综述殷跃辉审校 (重庆医科大学附属第二医院心血管内科，重庆400010) 【摘要】糖尿病作为心血管疾病的重要风险因素，也是老年人群中常见的慢性疾病之一。大部分心血管疾病如冠心病、高血 压、心肌病等随着病程的进展往往可发展为心房颤动。已有证据显示，糖尿病可通过影响心脏的自主神经重构、电重构及结构重构 诱发心房颤动；而在糖尿病患者中，心房颤动也是其全因死亡率和心血管发病率的独立危险因素。了解糖尿病在心房颤动发病中 的作用及各种降糖药对心房颤动的影响将有助于理解糖尿病和心房颤动的相关性，并更好地对合并心房颤动的糖尿病患者进行 管理。 【关键词】糖尿病；心房颤动；心房重构；降糖药物 ki．issn．1004—3934．2叭6．04．003 【中图分类号】R54 【文献标志码】A 【DoI】lo．16806／j．cn Effectof 2DiabetesMeUitusandDiabeticonAtrialFibriUation Type Drugs ZHANG Yuehui Ruoyu，YIN (上)ep口n批眦Q厂cordiofo∥，孤eseco蒯锄{fi。把d舶印玩f l0，劬i舳) Q厂C^D，醐i昭胁dicof踟溉倦毋，C九o，啪i增4000 meuitusisoneoffhemostcommonchmnicdiseasesforthesenior and oneofthemost 【AbstI’act】Diabetic populationpresents impo卜 for fant而skfactorScardioVascuIardisease．Mostcardiovasculardiseasesuchascomnary and arterydisease，hypertension will loatrial the of disease．Evidencehas thatAfisa and causeof develop fibrillation(Af)withpmgress primary pmven stmngindependent deathandcardiovascularindiabetic thatdiabetic could the ofAf mellitus initialionandmaintenance morbidity patients．Additionally pmmote the andstmctural oftheafrium．Itwill ustounderstandthe betweendiabetic by autonomic，elect“cal causing remodeUing help relationship mellitusandAfandmakebet【erdecisions the ofthese the ofAfinthe regardingmanagementpatientsbyreviewingpotentialpa