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中草药的提取与分离方法(国外英文资料)
中草药的提取与分离方法(国外英文资料)
Extraction and separation of Chinese herbal medicines
Chinese herbal medicines contain complex ingredients, both effective and ineffective, and toxic. In order to improve the therapeutic effect of Chinese herbal medicine, will do utmost from complex homogeneous or heterogeneous system to extract the effective components, and then by separating and removing impurity in order to reach the purpose of purifying and refining.
There are many methods for separating plant active ingredients, including the long history, the application of the solvent extraction, water vapor distillation, extraction, crystallization, adsorption, etc. With the development of science and technology, in the aspect of traditional Chinese medicine extract saw the emergence of many new technologies, new methods, mainly of supercritical fluid extraction technology, the ultrasonic extraction technology, microwave extraction, enzymatic and so on.
1.2.1 solvent extraction method
The choice of solvent: the key to the method of solvent extraction is choosing the appropriate solvent. When the solvent is chosen properly, it is easier to extract the necessary ingredients. It is important to note the following three points: the solvent is very solubility to the active component, and the solubility of impurity is small. The solvent cannot change with the composition of Chinese medicine; The solvent should be economical, easy to use and safe to use.
? The molecular structure of organic compounds is more hydrophilic, and its polarity is greater than oil; Some hydrophilic groups are small, and their polarity is small and dissoluble. The size of this hydrophilic, lipid, and its degree is directly related to the molecular structure of the compound. In general, two basic nucleus of the same composition, the greater the polarity of functional group in the molecule, or the more polar functional group, the entire molecular polarity is big, strong hydrophilicity, and lipotropy is weaker, the molecu
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