第 十三 章 铁代谢障碍性贫血及其实验诊断(国外英文资料).docVIP

第 十三 章 铁代谢障碍性贫血及其实验诊断(国外英文资料) In this chapter the examination site Red blood cell iron metabolism and function Test of iron metabolism and its application (iron metabolism test index) Causes of iron-deficiency anemia, clinical features and staging, laboratory diagnosis (laboratory examination and differential diagnosis) Laboratory diagnosis (laboratory examination and differential diagnosis) for erythrocyte anemia One, red blood cell iron metabolism and function Iron metabolism (1) the source and absorption of iron: only about 10% of the iron, or LMG, is absorbed in the daily diet. Iron is mainly absorbed by the duodenum of the digestive tract and the intestinal mucosa. (2) the transshipment and utilization of iron: the Fe2 + in the plasma, which has been converted to Fe3 + by the oxidation of copper and blue protein, and the combination of the iron and the egg to the tissues of the body. (3) storage and excretion of iron: iron in the form of ferrotein and hemosiderin. The number of pregnant women and children is more than doubled. The function of iron (1) make hemoglobin. (2) synthesis of ferroenzyme. (3) participate in important metabolism: the metabolism of catecholamine, the electron transfer of the enzyme in the mitochondrial REDOX reaction and the synthesis of DNA. (4) storage of iron: iron protein and iron-containing flavin. (5) synthetic myoglobin. 3. The metabolic disorders of iron: iron intake and excretion, utilization and loss on its own for dynamic adjustment and balance, any factor destroy the process of dynamic balance, the iron metabolism disorder. Iron is most likely to occur when iron is inadequately consumed or need to be increased. Plant-based foods are rich in iron, but not easily absorbed. After gastric bowel partial resection, absorption area decreases. Intestinal parasitic diseases such as the hemorrhagic anemia caused by hookworm disease are common in the countryside and can lead to iron deficiency. Acute or chronic hemolysis can cause seco