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癌症发病机理新说(国外英文资料)
癌症发病机理新说(国外英文资料)
The pathogenesis of cancer is new
Cancer has become the biggest killer of human health. There are more than 7.5 million cancer patients in China, and more than 1.3 million people die from cancer every year, and the incidence and death rate are increasing year by year.
The scientists on the mechanism of cancer puts forward four kinds of hypothesis: namely, gene mutation, immune surveillance, speaking according to the theory of alpha, beta cells to differentiate the naive said cell differentiation. It is now generally accepted that genetic mutations lead to cell differentiation, which is the discovery of the oncogene.
Carcinoma was first discovered in retrovirus cancer gene, and the virus in cancer gene called virus oncogenes, will exist in normal human organism and cells in cancer gene called proto-oncogenes or cell carcinoma. New cancer genes have been discovered in recent years. It is reported that more than 100 people have been found to have cancer. Under normal circumstances, although each contain cancer gene in the human body, but in a state of static or lower expression, not only harmless to cells, and plays an important role in maintaining normal cell function, does not make people suffer from cancer. If the external factors, such as environmental factors (diet and nutritional factors, chemical carcinogens), some viruses, such as radiation, carcinogenic factors invading the body of cancer gene will activate cells, causing deterioration of normal cells salty cancer cells.
According to current research, the characteristics of oncogenes can be summarized as follows: (1) widespread in the biosphere, from yeast to human cells. (2) in the course of evolution, the sequence of genes is highly conservative. (3) its function is expressed through the protein of its expression; They exist in normal cells not only harmless, but also for normal physiological function and regulation of cell growth and differentiation plays an important role, is cell develop
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