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托曲珠利治疗新孢子虫病
Veterinary Parasitology 172 (2010) 46–52
Contents lists available at ScienceDirect
Veterinary Parasitology
j o u rn al h omepage: w w w. elsev /locate/vet par
Effect of toltrazuril treatment in nursing piglets naturally infected with
Isospora suis
Vasilis Skampardonis a,b,∗ , Smaragda Sotiraki b , Polychronis Kostoulas a , Leonidas
Leontides a
a Laboratory of Epidemiology, Biostatistics and Animal Health Economics, University of Thessaly, 224 Trikalon st., 43100 Karditsa, Greece
b Veterinary Research Institute, National Agricultural Research Foundation, NAGREF Campus, PO Box 60272, 57001 Thermi, Greece
a r t i c l e i n f o a b s t r a c t
Article history: Isospora suis is an important parasitic infection in intensive pig production worldwide,
Received 11 January 2010 responsible for significant economic losses. In this study the efficacy of toltrazuril treat-
Received in revised form 16 March 2010
ment against isosporosis was evaluated, under field conditions and throughout the nursing
Accepted 16 April 2010
period, in reducing (i) the mean time to onset of diarrhoea and oocyst excretion, (ii) the
odds of diarrhoea and, (iii) the odds and level of oocyst excretion, adjusting for the het-
Keywords: erogeneity of I. suis infection among litters and across time. In a 300-sow farrow-to-finish
Isospora suis
Toltrazuril commercial operation, twenty-five litters were randomly allocated to receive to
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