英国纽卡斯尔大学药理学课件9.pptVIP

Basic pharmacokinetics Professor F Kamali Wolfson Unit of Clinical Pharmacology Basic pharmacokinetics Pharmacokinetics concept One compartment model Semi-logarithm drug concentration v time plot Measurement of drug pharmacokinetic parameters Basic pharmacokinetics Pharmacokinetics is a discipline that uses mathematical models to describe and predict drug amounts and concentrations in various body fluids that changes in these quantities over time. Absorption, distribution, biotransformation and elimination. Plasma drug concentration:- net results of the above processes taking place simultaneo