聚乙二醇―电解质溶液在肝性脑病中应用效果观察.docVIP

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聚乙二醇―电解质溶液在肝性脑病中应用效果观察.doc

聚乙二醇―电解质溶液在肝性脑病中应用效果观察

聚乙二醇―电解质溶液在肝性脑病中的应用效果观察   【摘要】 目的:观察分析聚乙二醇-电解质溶液在肝性脑病中的应用效果。方法:选取2015年4月-2016年3月来笔者所在医院诊治的50例肝性脑病患者,采用随机数字表法分为观察组和对照组,各25例。对照组采用常规乳果糖治疗,观察组采用聚乙二醇-电解质溶液治疗,观察比较两组的治疗效果与安全性。结果:治疗前两组患者血清生化、血氨比较,差异均无统计学意义(P0.05);而治疗后观察组以上各指标均显著低于对照组(P0.05)。结论:在常规治疗基础上,对肝性脑病患者给予聚乙二醇-电解质溶液治疗,能取得较乳果糖更佳的治疗效果,且安全性可,因此值得在临床治疗中推广应用 【关键词】 肝性脑病; 聚乙二醇-电解质溶液; 乳果糖; 效果; 安全性 中图分类号 R575 文献标识码 A 文章编号 1674-6805(2016)22-0009-03 【Abstract】 Objective:To observe and analyze the effect of polyethylene glycol-electrolyte solution in the treatment of hepatic encephalopathy.Method:50 patients with hepatic encephalopathy in our hospital from April 2015 to March 2016,they were divided into observation group and control group,according to the random number table method,25 cases in each group.The control group was treated with routine treatment,the observation group was treated with polyethylene glycol electrolyte solution,and the therapeutic effect and safety of the two groups were observed and compared.Result:Before treatment,two groups of patients with serum biochemistry,blood ammonia comparison,the differences were not statistically significant(P0.05), after treatment, the indexes of the observation group were significantly lower than those of the control group(P0.05).Conclusion:On the basis of conventional treatment,the patients with hepatic encephalopathy are treated with polyethylene glycol electrolyte solution,which could obtain better therapeutic effect, and the safety is good,so it is worth to be popularized in clinical treatment. 【Key words】 Hepatic encephalopathy; Polyethylene glycol-electrolyte solution; Lactulose; Efficacy; Safety First-authors address:The Peoples Hospital of Wuhua County,Wuhua 514400,China doi:10.14033/j.cnki.cfmr.2016.22.004 我国是世界公认的肝炎大国,病毒性肝炎发病数位居法定管理传染病的第一位,它严重危害我国人民健康的传染病[1]。肝炎慢性化易转为肝硬化、肝癌,其中肝性脑病作为肝硬化及肝癌患者的常见晚期并发症之一,其主要临床表现为意识障碍、行为失常和昏迷,出现一系列的神经精神异常,以上症状严重影响患者的生活质量,严重者甚至导致患者死亡[2-3],然而目前尚无一种疗效确切的治疗措施,因此寻找一种有效治疗肝性脑病的方法具有重要的现实意义。本试验中通过收集50例来笔者所在医院治疗的肝性脑病患者,随机分为对照组

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