O-GlcNAc 综述及其及 II 型糖尿病的关系.pdfVIP

O-GlcNAc 综述及其与II 型糖尿病的关系 鹿闲僧 此文档是本人提交的一份课堂作业，修正了之前文本参考文献格式的问题。文档内容仅供个人 参考。 Abstract ： O-GlcNAcylation is a ubiquitous posttranslational modification of nucleocytoplasmic proteins. In this review, I will interpret the extensive crosstalk exists between O-GlcNAcylation and phosphorylation, which regulates signaling in response to nutrients/stress. However, mechanisms regulating O-GlcNAcylation and phosphorylation are quite different as there is only one OGT in mammals while hundreds