益生菌酸奶临床试验文章.pdf

Korean J Gastroenterol Vol. 65 No. 4, 215-221 /10.4166/kjg.2015 pISSN 1598-9992 eISSN 2233-6869 ORIGINAL ARTICLE Effects of Probiotics on Gut Microbiota in Patients with Inflammatory Bowel Disease: A Double-blind, Placebo-controlled Clinical Trial 1 2 3 3 Mahdi Shadnoush, Rahebeh Shaker Hosseini, Ahad Khalilnezhad , Lida Navai , Hossein Goudarzi and Maryam Vaezjalali National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, Department of Immunology, 1 Medical School, Shahid Beheshti University of Medical Sciences , Department of Clinical Nutrition and Dietetics, National Nutrition 2 and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology , Department of Microbiology, Medical 3 School, Shahid Beheshti University of Medical Sciences , Tehran, Iran Background/Aims: Several clinical trials have revealed various advantages for probiotics in inflammatory bowel disease (IBD). The aim of this study was to further investigate the effects of probiotic yogurt consumption on gut microbiota in patients with this disease. Methods: A total of 305 participants were divided into three groups; group A (IBD patients receiving pro