瑞舒伐他汀和血脂康治疗高脂血症的疗效观察.pdfVIP

Pharmacy2014年第26卷第1期 天津药学Tianjin 药物与临床 瑞舒伐他汀和血脂康治疗高脂血症的疗效观察+ 胡毅利1，吴剑涓2 (1．天津市胸科医院，天津3000222；2．天津市环湖医院，天津300060) 摘要观察瑞舒伐他汀、血脂康治疗高脂血症的临床疗效。方法：80例确认高脂血症患者随机分为两组，每组40 例，分别予瑞舒伐他汀和血脂康治疗，观察8周，测定治疗前后的各项血脂指标，对其进行疗效评定，同时记录不良反应。 均未见明显不良反应。结论：瑞舒伐他汀和血脂康均可显著降低血脂，且以LDL降低最为显著。治疗期间两组丙氨酸氨 基转移酶(ALT)、尿素氮(BUN)、肌酐(cr)和肌酸磷酸激酶(CK)水平均无明显变化，未见严重不良反应。 关键词高脂血症，瑞舒伐他汀，血脂康 中图分类号：R972+．6文献标识码：A 文章编号：1006-5687(2014)01-0030-03 Clinical effectofrosuvastatinand on XuezhikanghyperHpidemia Hu Yilil，Wu Jianjuan2 Chest Huanhu 300060) (I．TianjinHospital，Tianjin300051；2．TianjinHospital，Tianjin ABSTRACT observethecurativeeffectofrosuvastatinand inthetreatmentof Objective：To Xuezhikang with were anddividedintotwo rosuvastatin—treatedandthe E诎tysubjectsdiagnosedhyperlipidemiarandomly groups，the group the wereobservedfor weeks．Theblood indexesbeforeandaftertreatmentwere Xuezhikang—treatedgroup．Allsubjects eight lipid to the measuredevaluatecurativeeffect．Theadversereactionswererecordedinthe withthebasline meantime．Result：Compared levelsobtainedtothe at the measllredtheendof treatmentcourese HDL—Cin- prior treatment，TC，TG，LDL—C decreased。while creasedinboth statisticaldifferenceWas groups．The foundbetweenthoseindexesmeasuredbeforeandafterthetreatment(P therewasno differencebetweenthet