肿瘤生物治疗中免疫活性细胞体外增殖活化的研究进展.pdfVIP

中华肿瘤防治杂志 2009 年 6 月第 16 卷第 11 期 　　CH IN J CAN CER PR EV TR EA T ,J une 2009 ,Vol 16 　No 11 ·875 · 综述 ·讲座 肿瘤生物治疗中免疫活性细胞体外增殖 活化的研究进展 潘晓明 , 　单保恩 河北医科大学第四医院科研中心 , 河北 石家庄 0500 11 Advance in re search of proliferation and activation of immune cells in vitro for biotherapy of cancer PA N X i aom i ng , S HA N B aoen R esea rch Center , Fou rt h H osp i t al of H ebei M e d ical Uni ve rs i ty , S hij i az h uang 0500 11 , P. R . Chi na 【摘要】　目的:总结近年来肿瘤生物治疗中免疫 [ ABSTRACT] 　OBJECTIVE : To review t he recent research 活性细胞体外增殖活化的研究进展 。方法 :应用 advance of p roliferation and activation of immune cell s i n PubMed 及 CN KI 期刊全文数据库以肿瘤生物治 v i t ro for biot herap y of cancer . METHODS : Lit erat ures about 疗 、树突状细胞 、细胞因子诱导的杀伤细胞 、细胞 DCs and CI K were ret rieved in PubMed and CN KI f rom 培养为关键词 ,检索 20000 1 - 200804 相关树突 2000 1 - 20084 . The docut erm s were biot herap y , DCs , 状细胞 、细胞因子诱导的杀伤细胞的文献 ,对资 CIK , cell s cult ure and so on , and t he languages were limit ed 料进行初选 ,并查看每篇文献后的引文 , 以文献 to Chinese and Engli sh resp ectively . The mat erial s relat ed to 内容与肿瘤生物治疗 、树突状细胞及细胞因子诱 biot herap y , t he cult ure of DCs and CI K were select ed p rima 导的杀伤细胞培养方法相关为纳入标准 。初选 rily and t he references of each article were looked for . Tot ally 有关数百篇关于树突状细胞及细胞因子诱导的 hundreds of relat ed articles were collect ed , 50 of t hem met 杀伤细胞培养方面的文章 ,根据纳入标准 ,精选 t he inclu sion crit eria , and finally 3 1 relat ed p ap er s were syn 50 篇 ,最后纳入分析 3 1 篇文献 。结果 :树突状细 t hesized . RESUL TS : DCs and CI