iData_探讨急性脑梗死患者颈动脉斑块稳定_省略_与D_二聚体浓度变化的相关性.pdfVIP

网络出版时间：2014-06-20 15:01 网络出版地址：/kcms/detail/11.4894.R1501.001.html 探讨急性脑梗死患者颈动脉斑块稳定性与 D-二聚体浓度变化的相关性研究 穆红艳，沈若宇，刘曼娇，袁志仙，岳 波 （中国人民解放军第411 医院特检科，上海 200081 ） [摘要] 目的：探讨颈动脉粥样硬化斑块稳定性与脑梗死患者D-二聚体变化的相关性。方法：收集136 例急性脑梗死患 者，应用彩色多普勒超声检测急性脑梗死患者颈动脉内- 中膜厚度（intima-media thickness ，IMT ）及粥样硬化斑块性质，采 用免疫比浊法测定D-二聚体浓度的含量并加以分析评价。结果：不稳定斑块组D-二聚体浓度明显高于稳定斑块组及无斑块 组，差异有统计学意义（P0.05 ）；稳定斑块组 D-二聚体浓度明显高于无斑块组，差异有统计学意义（P0.05 ）。结论：颈 动脉粥样硬化斑块稳定性与脑梗死患者D-二聚体的浓度变化具有相关性，为及时采取防治措施提供了超声依据。 [关键词] 彩色多普勒超声；急性脑梗死；内中膜厚度；粥样硬化斑块；D-二聚体 Correlaption study between the stability of carotid atherosclerotic plaques and the concentration of D-dimer in acute cerebral infraction patients MU Hong-yan,SHEN Ruo-yu,LIU Man -jiao,YUAN Zhi -xian,YUE Bo.Department of Special Examination,the No.411 Hospital of People’s Liberation Army,Shanghai,200081,China. [Abstract] Objective :To explore the correlaption between the stability of carotid atherosclerotic plaques and the concentration of D-dimer in acute cerebral infraction patients. Methods :The intima-media thickness (IMT) of carotid and the nature of carotid atherosclerotic plaques were evaluated by color dopple ultrasonorgraphy in 136 cases of acute cerebral infraction.Furthmore the concentration of D-dimer were determined by immunoturbidimetry. Results :The concentration of D-dimer in stable-plaques group were obviously increased than those in unstable-plaques group ，which was a statistical significance （P0.05 ）. The concentration of D-dimer in stable-plaques group were obviously increased than those in no-plaques group ，which was a statistical significance （P0.05 ）.Conclusion :The stability of carotid atherosclerotic plaques were relat