呼吸链电子传递线粒体氧化磷酸化偶联的重要限速步骤.PDFVIP

J ournal of Ti anj i n I nst it ute of P hy s ical Ed ucati on 15 1 2000 3 Vol. 15No. 1Mar, 20001 19 Sp ecial Lectures : 1 2 1 张　勇, 时庆德, 文　立 ( 1. , 300381) ( 2. 100084) : 线粒体氧化磷酸化解偶联和AT P 合成的降低可能是运动性疲劳的重要线粒体膜分子机制 一。作为这 一进程的重要限速步骤, 呼吸链电子传递可能与运动过程中线粒体氧化磷酸化解偶联密切 相关。并由此提出 “呼吸链电子传递可能是长时间运动中线粒体氧化磷酸化的重要限速步骤”假说。 : 线粒体呼吸链; 电子传递; 辅酶Q; 限速步骤; 氧化磷酸化; 耐力运动 : G804. 2; Q:A : 1005-0000( 2000) 01-001 -03 THE ELECTRON TRANSFERRING IN RESPIRATORY CHAIN: A KEY LIMITING STEP OF MITOCHONDRIAL OXIDATIVE PHOSPHORYLATION 1 2 1 , - , ZHANG Yong SHI Qing de WEN Li ( 1. Tianjin Research Institute of Sports M edicine, Tianjin 300381, China) ( 2. Dept. of Postgraduate, Beijing University of Physical Education, Beijing 100084, China) Abst ract : There w as indication that the un-couplingof mitochondrial oxidative phosphorylation and the decreased AT P re-synt hesis might be one of molecular mechanism s of mitochondrial mem brane for - . , exercise induced fatigue The electron transferring in respirat ory chain as a key limiting st ep of oxidat ive phosphorylation w as close associated w ith t he un-coupling of phosphorylation during the prolonged endurance exercise. Based on the evidence of exercise-induced fatigue, a hypothetical model that the electron transferring in respirat