新生儿黄疸的光疗干预指征及相关问题.pdfVIP

·综述· 新生儿黄疸的光疗干预指征及相关问题 姚强(综述)潘家华(审校) 【摘要1 新生儿黄疸或新生儿高胆红素血症是新生儿的一种常见现象，多数情况下是一个良性过程。 多种因素造成胆红素的产生和清除失衡即可引起高胆红素血症，部分患儿可发展成重度高胆红素血症，可 能会导致永久性的神经系统后遗症(核黄疸)。光疗是新生儿黄疸常见的治疗方法，应根据本地区、民族等 不同因素的流行病学特点，确定日龄或时龄相对应黄疽的干预值，并结合高危因素的评估，给予适时干预， 同时避免过度治疗。 【关键词】高胆红素血症；新生儿；胆红素脑病；光疗 Indicationsandrelated of interventionforneonatal YAO problemsphototherapy jaundiceQiang．PAN Province toAnhuiMedical ofPediatrics，Anhui Affiliated Jia—hua．Department Hospitaf University，Hefei 230001．China I Abstract】Neonataljaundiceor isaC01TtlTlonoccurrenceinnewborns．Mostcasesof hyperbilirubinemia neonatal havea canbebestunderstoodasabalancebetweenthe iaundice benigncourse．Hyperbilirubinemia andeliminationof amultitudeoffactorsandconditionseachof bilirubin．with these production affecting proces． animbalanceresults ofanincreasein ses．When because bilirubin(orthebilirubinload1 to circulating signifi— cause levels(severehyperbilirubinemia)，it neurologic cantlyhigh may permanent sequelae(kemicterus)，which is ifthe isidentifiedandtreated for isa preventablehyperbilirubinemiaearly appropriately．Phototherapyjaundice commontreatmentinneonatalmedicineandisusedto theneurotoxiceffectsof prevent bilirubin．Phototherapy on levels for shouldbebased totalserumbilirubinoftheinfant’sinhoursand hyperbilirubinemiaprimarly age otherfactorsthataffecttheriskofbilirubi