骨质疏松动物模型骨的拉伸、压缩、扭转实验研究.pdfVIP

生物医学工程研究 Joumal of Biomedical Engineering Research 骨质疏松动物模型骨的拉伸、压缩、扭转实验研究 罗 民?孟广伟，马洪顺A (吉林大学南岭校区工程力学系，长春 130022) 摘要;研究了正常大鼠和去势所致大鼠骨质疏松以电针、灸法、电针加雌激素、灸法加雌激素治疗姐大鼠 骨的拉伸、压缩、扭转力学性盾。选用36只280-32饨， 4-5 月龄Wistar 雌性大鼠，随机分为正常对照组6只， 模型姐6只，电针治疗组6只，灸法治疗姐6只，电针加雌激素治疗姐6只，灸法加雌;激素治疗纽6 只，对模型姐 大鼠于0周摘除其印巢。对正常对照姐和模型姐大鼠饲择13周后，以腹主动脉放血法处死大鼠，取大鼠脏骨进 行拉伸实验，取大鼠股骨进行扭转实验，取大鼠脏骨进行压缩实验。得出了各组大鼠骨的拉伸、压缩应力、应 变、弹性模最、扭转剪应力、扣特角等指标。结果表明:模型组拉仲、扭转、压缩力学性能指标均小于正常 姐。 关键诩:动物模型:骨质疏松;拉伸、压缩、扭转 申图分提号:R318 文献标识码:A 文章编号:1672-6278(2007)02-0131-04 The Experimental Study on Stretch、 Compress and Torsion of Osteoporosis Animal M，例lelRemedy LUO Min如IENG Guang-wei , MA Hong咄m (The Mechanical Department of Jìlin University,Changchun 130022,China) Abstract:To study the normal rat and the osteoporosis white rat caused by emasculation and the osseous stretch、 compress、 torsion、 mechanical property of white rat by acusector、 moxibustion、创trogen、 acusector with estrogen、 moxibustion with estrogen cure group. 刀lÏrty­ six wistar fema1e white mt wi世1280-32饨， four- five months old w创茸divi伽d randornly into norma1∞ntrol group (six),model group (six), acusector C旧e group (six) ,moxibustion cure 伊up (8坤， estrogen cure group (s凶，血cus剧。r with estrogen cure group (six) ,moxibustion withωtrogen c脚 group (six) , the white rats of model group were ex仙pat甜甜ire ov町in 0 week. Aften the white rats of normal control group and model group breeding 13 weeks ,they were putωdeath with abdonrinal aorta leting blood and the s加:tch experiment with white rat hurnerus and torsion testing WI由 white rat femora , compress shom experiment with white rat shin were proceeded. The indices of stretch、 compress stress 、 slraÏn elastic modulus、 ωrsional shearing stre础、 angle of torsion of white mts osseous of each group WI创e got.