菏泽市手足口病儿童病例肠道病毒71 型抗体水平分析.pdfVIP

主堡塞墼塑堕压堑垂堂苤查!!!!生兰旦筮丝鲞箜!塑璺!!!!!!!垦婴垦!垫!i竺!：垒趔!!!!!!!些丝：盟!：!·139· 病毒病诊断与治疗 菏泽市手足口病儿童病例肠道 病毒71型抗体水平分析 巨昆，姜林恩，李伟，任惠芹，井绪花，金宝辉 采集 【摘要】 目的分析手足口病低龄儿童病例的肠道病毒7l型(EV71)感染状况。方法 手足口病(HFMD)病例的血样，通过ELISA间接法检测EV7lIgG和IgM抗体并分析年龄、性别分布 情况。结果收集到159例HFMD儿童病例的血样和资料，年龄为l一5周岁，平均EV7llgG抗体阳 性率为63．5％，无性别差异，平均lgM抗体阳性率为12．O％；EV71IgG阳性率随着年龄增长而呈降低 趋势，男奄的IgM阳性率显著高于女童。结论本次HFMD疫情的病原体是EV7l，男性儿童的EV71 感染发病率高于女性儿童，结果可为HFMD防治提供参考依据。 【主题词】 手足口病；肠道病毒7l型，人；免疫球蛋白G；免疫球蛋白M the levelofEnterovirus71aboutchildrencasesofhand-food-mousedisease Analyzeantibody Bao—hui．‘Heze outbreakJUKun‘。JIANGLin—en，LI Xu—hua，JIN Wei，RENHui—qing．JING ci￡y Blood Provence，274003，China Center，Shandong To theEnterovirus71infectiousstatusabout casesofhand- 【Abstract】Objectiveanalyze probably ofHFDM and foot—mouse Collecttheblood children cases disease(HFMD)．Methodssamples probably testthe the and distribution．ResultsWecollected159 age IgG，IgMantibodybyELISA，analyzedgender EV7 blood ofchildren caseswhoarelto5 old．The 1 rateis samples probably years averagelgGpositive of is12．O％．The rateofEV71 isdecrease EV71 63．5％．which lgM positive IgG byaged．Male’SIgM rateis thanfemale’S The ofthiscaseofHFMDoutbreak positive higher significantly．Conclusionpathogen is EV71infectiousandincidenceare than resultofthis EV71．Male’S higher female’S．The investigation could informationtoHFMDdiseasecontr01． provide 7 andmo