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                婴儿五联疫苗打针说明
                    
                               Centers for Disease Control and Prevention (CDC) 
                  National Center for Immunization and Respiratory Diseases (NCIRD) 
                                                         Atlanta, GA 
                                                        May 11, 2012 
                                                                                       ®                     ® 
Guidance for Vaccinating Children during the 2012 Pentacel   and Daptacel   Shortage 
Sanofi Pasteur’s Pentacel (DTaP-IPV/Hib) and Daptacel (DTaP) are expected to be in short  
supply throughout the summer of 2012.  Practices using these vaccines may need to find  
alternatives during the shortage.    
  
Providers should continue to follow the recommended immunization schedule and ensure that  
patients receive all recommended doses of DTaP, Hib, and polio vaccines.    
  
Vaccines for Children (VFC) providers should contact their state or local immunization  
program for guidance about ordering vaccines.   
  
Options include: 
  
 · Using DTaP, IPV, and Hib vaccines to complete a series begun with Pentacel.  There is a  
     sufficient supply of these products to meet the anticipated demand.    
      
 · Other combination vaccines containing DTaP and Hib vaccines may also be used to  
    complete the series.    
  
Considerations when changing vaccine products: 
 · The Advisory Committee on Immunization Practices (ACIP) recommends using the same  
    brand of vaccine for all doses of a vaccination series, when feasible. If providers do not  
    know or do not have available the brand of vaccine previously administered, another brand  
    may be used.   
      
 · With the exception of Hiberix, which is licensed only for use as the last dose (booster) in the  
    Hib series, Hib vaccines are interchangeable. If different brands of a vaccine require  
    different numbers of doses, use the higher number when mixing brands. The Hib vaccine  
    c
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