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中南大学学报（医学版） 2012, 37(6) ; J Cent South Univ (Med Sci) 633 CASE ANALYSIS · · ·临床病例讨论 · 肾上腺皮质嗜酸细胞腺瘤 3 例诊断和治疗并文献复习 宋伟，杨金瑞，黄莉 ( 中南大学湘雅二医院泌尿外科，长沙 410011) [ 摘要 ] 为探讨肾上腺皮质嗜酸细胞腺瘤的诊断和治疗。本研究回顾性分析 3 例肾上腺皮质嗜酸细胞腺瘤的临床 资料并复习相关文献。3 例患者中 1 例表现为女性男性化，其余 2 例无特异表现。肿瘤包膜完整，呈非浸润性生长。 光镜下，肿瘤细胞胞质丰富，嗜酸性，未见明显核分裂相和坏死。术后严格随访，3 例均未见肿瘤复发和转移。肾上 腺皮质嗜酸细胞腺瘤非常罕见，且大多数为良性，术前难以明确诊断，治疗首选手术切除，术后应严格随访。 [ 关键词 ] 肾上腺肿瘤；嗜酸细胞瘤；良性；功能性 DOI:10.3969/j.issn.1672-7347.2012.06.016 Diagnosis and treatment of three cases of adrenocortical oncocytoma and a literature review SONG Wei, YANG Jinrui, HUANG Li (Department of Urology, Second Xiangya Hospital, Central South University, Changsha 410011, China) ABSTRACT To investigate the diagnosis and surgical treatment of adrenocortical oncocytoma. The clinical data from three cases of adrenocortical oncocytomas (ACOs) were retrospectively analyzed and discussed in light of the relevant literature. In these three cases, one presented with virilization, while the other two cases had no typical clinical features. The tumor was completely encapsulated and was non-invasive. Microscopically, the tumor cells showed neither mitosis nor necrosis, with abundant eosinophilic cytoplasm. No recurrence or metastasis was discovered after close follow-up observation for 12–24 months. Adrenocortical ACOs are rather rare, an